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Early de novo DNA methylation and prolonged demethylation in the muscle lineage

Myogenic cell cultures derived from muscle biopsies are excellent models for human cell differentiation. We report the first comprehensive analysis of myogenesis-specific DNA hyper- and hypo-methylation throughout the genome for human muscle progenitor cells (both myoblasts and myotubes) and skeleta...

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Detalles Bibliográficos
Autores principales: Tsumagari, Koji, Baribault, Carl, Terragni, Jolyon, Varley, Katherine E., Gertz, Jason, Pradhan, Sirharsa, Badoo, Melody, Crain, Charlene M., Song, Lingyun, Crawford, Gregory E., Myers, Richard M., Lacey, Michelle, Ehrlich, Melanie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3669123/
https://www.ncbi.nlm.nih.gov/pubmed/23417056
http://dx.doi.org/10.4161/epi.23989

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