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In Vivo Visualization of Notch1 Proteolysis Reveals the Heterogeneity of Notch1 Signaling Activity in the Mouse Cochlea
Mechanosensory hair cells (HCs) and surrounding supporting cells (SCs) in the mouse cochlea are important for hearing and are derived from the same prosensory progenitors. Notch1 signaling plays dual but contrasting and age-dependent roles in mouse cochlear development: early lateral induction and s...
Autores principales: | Liu, Zhiyong, Liu, Zhenyi, Walters, Bradley J., Owen, Thomas, Kopan, Raphael, Zuo, Jian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3669271/ https://www.ncbi.nlm.nih.gov/pubmed/23741415 http://dx.doi.org/10.1371/journal.pone.0064903 |
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