Mapping the Epitopes of a Neutralizing Antibody Fragment Directed against the Lethal Factor of Bacillus anthracis and Cross-Reacting with the Homologous Edema Factor

The lethal toxin (LT) of Bacillus anthracis, composed of the protective antigen (PA) and the lethal factor (LF), plays an essential role in anthrax pathogenesis. PA also interacts with the edema factor (EF, 20% identity with LF) to form the edema toxin (ET), which has a lesser role in anthrax pathog...

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Detalles Bibliográficos
Autores principales: Thullier, Philippe, Avril, Arnaud, Mathieu, Jacques, Behrens, Christian K., Pellequer, Jean-Luc, Pelat, Thibaut
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3669279/
https://www.ncbi.nlm.nih.gov/pubmed/23741517
http://dx.doi.org/10.1371/journal.pone.0065855

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