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Improved Production Process for Native Outer Membrane Vesicle Vaccine against Neisseria meningitidis
An improved detergent-free process has been developed to produce vaccine based on native outer membrane vesicles (NOMV) against Neisseria meningitidis serogroup B. Performance was evaluated with the NonaMen vaccine concept, which provides broad coverage based on nine distinct PorA antigens. Scalable...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3669287/ https://www.ncbi.nlm.nih.gov/pubmed/23741478 http://dx.doi.org/10.1371/journal.pone.0065157 |