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Obestatin Enhances In Vitro Generation of Pancreatic Islets through Regulation of Developmental Pathways

Availability of large amounts of in vitro generated β-cells may support replacement therapy in diabetes. However, methods to obtain β-cells from stem/progenitor cells are limited by inefficient endocrine differentiation. We have recently shown that the ghrelin gene product obestatin displays benefic...

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Detalles Bibliográficos
Autores principales: Baragli, lessandra, Grande, Cristina, Gesmundo, Iacopo, Settanni, Fabio, Taliano, Marina, Gallo, Davide, Gargantini, Eleonora, Ghigo, Ezio, Granata, Riccarda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3669302/
https://www.ncbi.nlm.nih.gov/pubmed/23741322
http://dx.doi.org/10.1371/journal.pone.0064374