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Genome-Wide Small RNA Sequencing and Gene Expression Analysis Reveals a microRNA Profile of Cancer Susceptibility in ATM-Deficient Human Mammary Epithelial Cells
Deficiencies in the ATM gene are the underlying cause for ataxia telangiectasia, a syndrome characterized by neurological, motor and immunological defects, and a predisposition to cancer. MicroRNAs (miRNAs) are useful tools for cancer profiling and prediction of therapeutic responses to clinical reg...
Autores principales: | Hesse, Jill E., Liu, Liwen, Innes, Cynthia L., Cui, Yuxia, Palii, Stela S., Paules, Richard S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3669333/ https://www.ncbi.nlm.nih.gov/pubmed/23741392 http://dx.doi.org/10.1371/journal.pone.0064779 |
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