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Evaluation of ALK Rearrangement in Chinese Non-Small Cell Lung Cancer Using FISH, Immunohistochemistry, and Real-Time Quantitative RT- PCR on Paraffin-Embedded Tissues

Patients with ALK gene rearrangements often manifest dramatic responses to crizotinib, an ALK inhibitor. Accurate identification of patients with ALK-positive non-small cell lung cancer (NSCLC) is essential for the clinical application of ALK-targeted therapy. However, assessing EML4-ALK rearrangeme...

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Detalles Bibliográficos
Autores principales:	Zhang, Yun-Gang, Jin, Mu-Lan, Li, Li, Zhao, Hong-Ying, Zeng, Xuan, Jiang, Lei, Wei, Ping, Diao, Xiao-Li, Li, Xue, Cao, Qing, Tian, Xin-Xia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3669339/ https://www.ncbi.nlm.nih.gov/pubmed/23741400 http://dx.doi.org/10.1371/journal.pone.0064821

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