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Insulin Receptor Substrate 2 Is Required for Testicular Development

Insulin receptor substrate (IRS) proteins are key mediators of insulin and insulin-like growth factor (IGF) signalling. In mice, deletion of Irs1 is associated with profound growth retardation and increased longevity whereas Irs2-deficiency causes diabetes and female infertility. Clinical studies su...

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Detalles Bibliográficos
Autores principales:	Griffeth, Richard J., Carretero, Jose, Burks, Deborah J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3669358/ https://www.ncbi.nlm.nih.gov/pubmed/23741292 http://dx.doi.org/10.1371/journal.pone.0062103

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