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Increased Beta2-Adrenoceptors in Doxorubicin-Induced Cardiomyopathy in Rat
BACKGROUND: The toxicity of doxorubicin, leading to an irreversible heart failure, limits its use as chemotherapeutic agent. The beneficial effects of early administration of β-blocker were reported in patients with heart failure due to doxorubicin, suggesting an important role of β-adrenoceptors (β...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3669386/ https://www.ncbi.nlm.nih.gov/pubmed/23741376 http://dx.doi.org/10.1371/journal.pone.0064711 |