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TGF-β Enhanced IL-21-Induced Differentiation of Human IL-21-Producing CD4(+) T Cells via Smad3
IL-21 has pleiotropic effects on innate and adaptive immune response, and plays an important role in the development of autoimmune disease and antitumor activity. It has been reported that IL-21 is produced by CD4(+) T cells and NKT cells. However, the differentiation of IL-21-producing CD4(+) T cel...
Autores principales: | Liu, Yun, Yu, Sifei, Li, Zitao, Ma, Jiangjun, Zhang, Yannan, Wang, Hui, Yang, Binyan, Wu, Changyou |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3669387/ https://www.ncbi.nlm.nih.gov/pubmed/23741351 http://dx.doi.org/10.1371/journal.pone.0064612 |
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