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Simultaneous Screening and Validation of Effective Zinc Finger Nucleases in Yeast
Zinc finger nucleases (ZFNs) have been successfully used for genome modification in various cell types and species. However, construction of an effective ZFN remained challenging. Previous studies all focused on obtaining specific zinc finger proteins (ZFPs) first via bacterial 2-hybrid approach, an...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3669427/ https://www.ncbi.nlm.nih.gov/pubmed/23741369 http://dx.doi.org/10.1371/journal.pone.0064687 |