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Explant cultures of Rpe65(−/−) mouse retina: a model to investigate cone opsin trafficking
PURPOSE: In the absence of 11-cis retinal (e.g., Rpe65(−/−)), the chromophore for all pigments, cone opsins are mislocalized in vivo. Using the systemic application of 11-cis retinal, appropriate protein localization can be promoted. Here, we asked whether explant cultures of Rpe65(−/−) mouse retina...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Molecular Vision
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3669539/ https://www.ncbi.nlm.nih.gov/pubmed/23734084 |