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Binding mode prediction of biologically active compounds from plant Salvia Miltiorrhiza as integrase inhibitor
Integrase (IN), an essential enzyme for HIV-1 replication, has been targeted in antiretroviral drug therapy. The emergence of HIV-1 variants clinically resistant to antiretroviral agents has lead to the development of alternative IN inhibitors. In the present work, binding modes of a high potent IN...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Biomedical Informatics
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3670126/ https://www.ncbi.nlm.nih.gov/pubmed/23750093 http://dx.doi.org/10.6026/97320630009426 |