Cargando…

Modulation of human JAK-STAT pathway signaling by functionally conserved regulators

Both the core JAK-STAT pathway components and their in vivo roles have been widely conserved between vertebrates and invertebrate models such as Drosophila melanogaster. Misregulation of JAK-STAT pathway activity has also been identified as a key factor in the development of multiple human malignanc...

Descripción completa

Detalles Bibliográficos
Autores principales: Müller, Patrick, Pugazhendhi, Dhamayanthi, Zeidler, Martin P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3670133/
https://www.ncbi.nlm.nih.gov/pubmed/24058749
http://dx.doi.org/10.4161/jkst.18006