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How worms survive desiccation: Trehalose pro water

While life requires water, many organisms, known as anhydrobiotes, can survive in the absence of water for extended periods of time. Although discovered 300 years ago, we know very little about the fascinating phenomenon of anhydrobiosis. In this paper, we summarize our previous findings on the desi...

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Detalles Bibliográficos
Autores principales: Erkut, Cihan, Penkov, Sider, Fahmy, Karim, Kurzchalia, Teymuras V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3670174/
https://www.ncbi.nlm.nih.gov/pubmed/24058825
http://dx.doi.org/10.4161/worm.19040
Descripción
Sumario:While life requires water, many organisms, known as anhydrobiotes, can survive in the absence of water for extended periods of time. Although discovered 300 years ago, we know very little about the fascinating phenomenon of anhydrobiosis. In this paper, we summarize our previous findings on the desiccation tolerance of the Caenorhabditis elegans dauer larva. A special emphasis is given to the role of trehalose in protecting membranes against desiccation. We also propose a simple mechanism for this process.