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The interaction of octopamine and neuropeptides to slow aversive responses in C. elegans mimics the modulation of chronic pain in mammals
Octopamine (OA) appears to function as the invertebrate counterpart of norepinephrine (NE) in the modulation of a number of key behaviors. In C. elegans, OA signaling is complex, mediated by at least three distinct α-adrenergic-like receptors and appears to activate more global peptidergic signaling...
Autores principales: | Mills, Holly, Hapiak, Vera, Harris, Gareth, Summers, Phillip, Komuniecki, Richard |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Landes Bioscience
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3670219/ https://www.ncbi.nlm.nih.gov/pubmed/24058849 http://dx.doi.org/10.4161/worm.20467 |
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