The JAK-STAT pathway and hematopoietic stem cells from the JAK2 V617F perspective

Janus kinases (JAKs) are non-receptor tyrosine kinases essential for activation of signaling mediated by cytokine receptors that lack catalytic activity, including receptors for erythropoietin, thrombopoietin, most interleukins and interferon. Upon hormone binding, JAKs phosphorylate tyrosine residu...

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Detalles Bibliográficos
Autores principales: Staerk, Judith, Constantinescu, Stefan N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2012
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3670242/
https://www.ncbi.nlm.nih.gov/pubmed/24058768
http://dx.doi.org/10.4161/jkst.22071

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3670242/
https://www.ncbi.nlm.nih.gov/pubmed/24058768
http://dx.doi.org/10.4161/jkst.22071

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