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The regulation of inflammation by interferons and their STATs
Interferons (IFN) are subdivided into type I IFN (IFN-I, here synonymous with IFN-α/β), type II (IFN-γ) and type III IFN (IFN-III/IFN-λ) that reprogram nuclear gene expression through STATs 1 and 2 by forming STAT1 dimers (mainly IFN-γ) or the ISGF3 complex, a STAT1-STAT2-IRF9 heterotrimer (IFN-I an...
Autores principales: | Rauch, Isabella, Müller, Mathias, Decker, Thomas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Landes Bioscience
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3670275/ https://www.ncbi.nlm.nih.gov/pubmed/24058799 http://dx.doi.org/10.4161/jkst.23820 |
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