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C. elegans survivors without telomerase
In most eukaryotic organisms with a linear genome, the telomerase complex is essential for telomere maintenance and, thus, for genomic integrity. Proper telomerase function in stem and germ cell populations counteracts replication-dependent telomere shortening. On the other hand, repression of telom...
Autores principales: | Lackner, Daniel H., Karlseder, Jan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Landes Bioscience
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3670455/ https://www.ncbi.nlm.nih.gov/pubmed/24058854 http://dx.doi.org/10.4161/worm.21073 |
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