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Effects of mutations in mitochondrial dynamics-related genes on the mitochondrial response to ultraviolet C radiation in developing Caenorhabditis elegans
We recently found that genes involved in mitochondrial dynamics and autophagy are required for removal of UVC-induced mitochondrial DNA damage. However, drp-1 and pink-1, unlike the autophagy and fusion genes tested, were not necessary for larval development after exposure. We hypothesized that incr...
Autores principales: | Bess, Amanda S., Leung, Maxwell C.K., Ryde, Ian T., Rooney, John P., Hinton, David E., Meyer, Joel N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Landes Bioscience
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3670464/ https://www.ncbi.nlm.nih.gov/pubmed/24058863 http://dx.doi.org/10.4161/worm.23763 |
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