Depletion of the ER chaperone ENPL-1 sensitizes C. elegans to the anticancer drug cisplatin

Cisplatin is an essential chemotherapeutic drug in the treatment of many cancers. Its use, however, is limited by the development of resistance in many tumors. The ability to re-sensitize resistant tumors could significantly strengthen cisplatin therapy in patients. Caenorhabditis elegans is a suita...

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Detalles Bibliográficos
Autores principales: Natarajan, Balasubramanian, Gaur, Rahul, Hemmingsson, Oskar, Kao, Gautam, Naredi, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3670465/
https://www.ncbi.nlm.nih.gov/pubmed/24058864
http://dx.doi.org/10.4161/worm.24059

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3670465/
https://www.ncbi.nlm.nih.gov/pubmed/24058864
http://dx.doi.org/10.4161/worm.24059

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