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Depletion of the ER chaperone ENPL-1 sensitizes C. elegans to the anticancer drug cisplatin
Cisplatin is an essential chemotherapeutic drug in the treatment of many cancers. Its use, however, is limited by the development of resistance in many tumors. The ability to re-sensitize resistant tumors could significantly strengthen cisplatin therapy in patients. Caenorhabditis elegans is a suita...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Landes Bioscience
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3670465/ https://www.ncbi.nlm.nih.gov/pubmed/24058864 http://dx.doi.org/10.4161/worm.24059 |