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Evaluation of a new panel of six mononucleotide repeat markers for the detection of DNA mismatch repair-deficient tumours

BACKGROUND: Microsatellite instability (MSI) is a molecular phenotype due to defective DNA mismatch repair (MMR) system. It is used to predict outcome of colorectal tumours and to screen tumours for Lynch syndrome (LS). A pentaplex panel composed of five mononucleotide markers has been largely recom...

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Detalles Bibliográficos
Autores principales:	Pagin, A, Zerimech, F, Leclerc, J, Wacrenier, A, Lejeune, S, Descarpentries, C, Escande, F, Porchet, N, Buisine, M-P
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2013
Materias:	Molecular Diagnostics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3670492/ https://www.ncbi.nlm.nih.gov/pubmed/23652311 http://dx.doi.org/10.1038/bjc.2013.213

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