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Assessment of DNA methylation status in early stages of breast cancer development

BACKGROUND: Molecular pathways determining the malignant potential of premalignant breast lesions remain unknown. In this study, alterations in DNA methylation levels were monitored during benign, premalignant and malignant stages of ductal breast cancer development. METHODS: To study epigenetic eve...

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Detalles Bibliográficos
Autores principales: van Hoesel, A Q, Sato, Y, Elashoff, D A, Turner, R R, Giuliano, A E, Shamonki, J M, Kuppen, P J K, van de Velde, C J H, Hoon, D S B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3670495/
https://www.ncbi.nlm.nih.gov/pubmed/23652305
http://dx.doi.org/10.1038/bjc.2013.136