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Pancreatic Metastasis from Mixed Adenoneuroendocrine Carcinoma of the Uterine Cervix: A Case Report
Metastatic cancers of the pancreas are rare, accounting for approximately 2–4% of all pancreatic malignancies. Renal cell carcinoma is the most common solid tumor that metastasizes to the pancreas. Here, we present a case of uterine cervical carcinoma metastasizing to the pancreas and review the lit...
Autores principales: | , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
S. Karger AG
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3670638/ https://www.ncbi.nlm.nih.gov/pubmed/23741220 http://dx.doi.org/10.1159/000351308 |
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author | Nishimura, Chihiro Naoe, Hideaki Hashigo, Shunpei Tsutsumi, Hideharu Ishii, Shotaro Konoe, Takeyasu Watanabe, Takehisa Shono, Takashi Sakurai, Kouichi Takaishi, Kiyomi Ikuta, Yoshiaki Chikamoto, Akira Tanaka, Motohiko Iyama, Ken-ichi Baba, Hideo Katabuchi, Hidetaka Sasaki, Yutaka |
author_facet | Nishimura, Chihiro Naoe, Hideaki Hashigo, Shunpei Tsutsumi, Hideharu Ishii, Shotaro Konoe, Takeyasu Watanabe, Takehisa Shono, Takashi Sakurai, Kouichi Takaishi, Kiyomi Ikuta, Yoshiaki Chikamoto, Akira Tanaka, Motohiko Iyama, Ken-ichi Baba, Hideo Katabuchi, Hidetaka Sasaki, Yutaka |
author_sort | Nishimura, Chihiro |
collection | PubMed |
description | Metastatic cancers of the pancreas are rare, accounting for approximately 2–4% of all pancreatic malignancies. Renal cell carcinoma is the most common solid tumor that metastasizes to the pancreas. Here, we present a case of uterine cervical carcinoma metastasizing to the pancreas and review the literature regarding this rare event. A 44-year-old woman with a uterine cervical tumor had undergone radical hysterectomy and had been diagnosed pathologically with stage Ib mixed adenoneuroendocrine carcinoma in 2004. She underwent concurrent radiotherapy and chemotherapy postoperatively. Pulmonary metastases subsequently appeared in 2008 and 2011, and she underwent complete resection of the lung tumors by video-assisted thoracic surgery. Although she was followed up without any treatment and with no other recurrences, positron emission tomography revealed an area of abnormal uptake within the pancreatic body in 2012. Enhanced computed tomography demonstrated a 20-mm lesion in the pancreatic body and upstream pancreatic duct dilatation. Endoscopic ultrasonography-guided fine needle aspiration was performed and pathological examination suggested neuroendocrine carcinoma (NEC). On the basis of these results and the patient's oncological background, lesions in the pancreatic body were diagnosed as secondary metastasis from the cervical carcinoma that had been treated 8 years earlier. No other distant metastases were visualized, and the patient subsequently underwent middle pancreatectomy. Pathological examination showed NEC consistent with pancreatic metastasis from the uterine cervical carcinoma. The patient has survived 7 months since the middle pancreatectomy without any signs of local recurrence or other metastatic lesions. |
format | Online Article Text |
id | pubmed-3670638 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | S. Karger AG |
record_format | MEDLINE/PubMed |
spelling | pubmed-36706382013-06-05 Pancreatic Metastasis from Mixed Adenoneuroendocrine Carcinoma of the Uterine Cervix: A Case Report Nishimura, Chihiro Naoe, Hideaki Hashigo, Shunpei Tsutsumi, Hideharu Ishii, Shotaro Konoe, Takeyasu Watanabe, Takehisa Shono, Takashi Sakurai, Kouichi Takaishi, Kiyomi Ikuta, Yoshiaki Chikamoto, Akira Tanaka, Motohiko Iyama, Ken-ichi Baba, Hideo Katabuchi, Hidetaka Sasaki, Yutaka Case Rep Oncol Published online: May, 2013 Metastatic cancers of the pancreas are rare, accounting for approximately 2–4% of all pancreatic malignancies. Renal cell carcinoma is the most common solid tumor that metastasizes to the pancreas. Here, we present a case of uterine cervical carcinoma metastasizing to the pancreas and review the literature regarding this rare event. A 44-year-old woman with a uterine cervical tumor had undergone radical hysterectomy and had been diagnosed pathologically with stage Ib mixed adenoneuroendocrine carcinoma in 2004. She underwent concurrent radiotherapy and chemotherapy postoperatively. Pulmonary metastases subsequently appeared in 2008 and 2011, and she underwent complete resection of the lung tumors by video-assisted thoracic surgery. Although she was followed up without any treatment and with no other recurrences, positron emission tomography revealed an area of abnormal uptake within the pancreatic body in 2012. Enhanced computed tomography demonstrated a 20-mm lesion in the pancreatic body and upstream pancreatic duct dilatation. Endoscopic ultrasonography-guided fine needle aspiration was performed and pathological examination suggested neuroendocrine carcinoma (NEC). On the basis of these results and the patient's oncological background, lesions in the pancreatic body were diagnosed as secondary metastasis from the cervical carcinoma that had been treated 8 years earlier. No other distant metastases were visualized, and the patient subsequently underwent middle pancreatectomy. Pathological examination showed NEC consistent with pancreatic metastasis from the uterine cervical carcinoma. The patient has survived 7 months since the middle pancreatectomy without any signs of local recurrence or other metastatic lesions. S. Karger AG 2013-05-09 /pmc/articles/PMC3670638/ /pubmed/23741220 http://dx.doi.org/10.1159/000351308 Text en Copyright © 2013 by S. Karger AG, Basel http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article licensed under the terms of the Creative Commons Attribution-NonCommercial 3.0 Unported license (CC BY-NC) (www.karger.com/OA-license), applicable to the online version of the article only. Users may download, print and share this work on the Internet for noncommercial purposes only, provided the original work is properly cited, and a link to the original work on http://www.karger.com and the terms of this license are included in any shared versions. |
spellingShingle | Published online: May, 2013 Nishimura, Chihiro Naoe, Hideaki Hashigo, Shunpei Tsutsumi, Hideharu Ishii, Shotaro Konoe, Takeyasu Watanabe, Takehisa Shono, Takashi Sakurai, Kouichi Takaishi, Kiyomi Ikuta, Yoshiaki Chikamoto, Akira Tanaka, Motohiko Iyama, Ken-ichi Baba, Hideo Katabuchi, Hidetaka Sasaki, Yutaka Pancreatic Metastasis from Mixed Adenoneuroendocrine Carcinoma of the Uterine Cervix: A Case Report |
title | Pancreatic Metastasis from Mixed Adenoneuroendocrine Carcinoma of the Uterine Cervix: A Case Report |
title_full | Pancreatic Metastasis from Mixed Adenoneuroendocrine Carcinoma of the Uterine Cervix: A Case Report |
title_fullStr | Pancreatic Metastasis from Mixed Adenoneuroendocrine Carcinoma of the Uterine Cervix: A Case Report |
title_full_unstemmed | Pancreatic Metastasis from Mixed Adenoneuroendocrine Carcinoma of the Uterine Cervix: A Case Report |
title_short | Pancreatic Metastasis from Mixed Adenoneuroendocrine Carcinoma of the Uterine Cervix: A Case Report |
title_sort | pancreatic metastasis from mixed adenoneuroendocrine carcinoma of the uterine cervix: a case report |
topic | Published online: May, 2013 |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3670638/ https://www.ncbi.nlm.nih.gov/pubmed/23741220 http://dx.doi.org/10.1159/000351308 |
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