Cargando…
Lepr(db/db) Mice with Senescence Marker Protein-30 Knockout (Lepr(db/db)Smp30(Y/−)) Exhibit Increases in Small Dense-LDL and Severe Fatty Liver Despite Being Fed a Standard Diet
BACKGROUND/AIMS: The senescence marker protein-30 (SMP30) is a 34 kDa protein originally identified in rat liver that shows decreased levels with age. Several functional studies using SMP30 knockout (Smp30(Y/−)) mice established that SMP30 functions as an antioxidant and protects against apoptosis....
Autores principales: | Kondo, Yoshitaka, Hasegawa, Goji, Okada, Hiroshi, Senmaru, Takafumi, Fukui, Michiaki, Nakamura, Naoto, Sawada, Morio, Kitawaki, Jo, Okanoue, Takeshi, Kishimoto, Yuki, Amano, Akiko, Maruyama, Naoki, Obayashi, Hiroshi, Ishigami, Akihito |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3670834/ https://www.ncbi.nlm.nih.gov/pubmed/23755269 http://dx.doi.org/10.1371/journal.pone.0065698 |
Ejemplares similares
-
Galantamine improves glycemic control and diabetic nephropathy in Lepr(db/db) mice
por: Meng, Qinghe, et al.
Publicado: (2023) -
Stem Cell Replacement Improves Expression of SMP30 in db/db Mice
por: Li, Ming, et al.
Publicado: (2015) -
Overexpression of lipoic acid synthase gene alleviates diabetic nephropathy of Lepr(db/db) mice
por: Zhao, Yingzheng, et al.
Publicado: (2021) -
Metformin Suppresses Diethylnitrosamine-Induced Liver Tumorigenesis in Obese and Diabetic C57BL/KsJ-+Lepr(db)/+Lepr(db) Mice
por: Ohno, Tomohiko, et al.
Publicado: (2015) -
Silk Fibroin Promotes the Regeneration of Pancreatic β-Cells in the C57BL/KsJ-Lepr(db/db) Mouse
por: Park, So-young, et al.
Publicado: (2020)