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Müller Cell Reactivity in Response to Photoreceptor Degeneration in Rats with Defective Polycystin-2

BACKGROUND: Retinal degeneration in transgenic rats that express a mutant cilia gene polycystin-2 (CMV-PKD2(1/703)HA) is characterized by initial photoreceptor degeneration and glial activation, followed by vasoregression and neuronal degeneration (Feng et al., 2009, PLoS One 4: e7328). It is unknow...

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Detalles Bibliográficos
Autores principales: Vogler, Stefanie, Pannicke, Thomas, Hollborn, Margrit, Grosche, Antje, Busch, Stephanie, Hoffmann, Sigrid, Wiedemann, Peter, Reichenbach, Andreas, Hammes, Hans-Peter, Bringmann, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3670868/
https://www.ncbi.nlm.nih.gov/pubmed/23755094
http://dx.doi.org/10.1371/journal.pone.0061631