Scanning a DNA Molecule for Bound Proteins Using Hybrid Magnetic and Optical Tweezers

The functional state of the genome is determined by its interactions with proteins that bind, modify, and move along the DNA. To determine the positions and binding strength of proteins localized on DNA we have developed a combined magnetic and optical tweezers apparatus that allows for both sensiti...

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Detalles Bibliográficos
Autores principales: van Loenhout, Marijn T. J., De Vlaminck, Iwijn, Flebus, Benedetta, den Blanken, Johan F., Zweifel, Ludovit P., Hooning, Koen M., Kerssemakers, Jacob W. J., Dekker, Cees
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3670887/
https://www.ncbi.nlm.nih.gov/pubmed/23755219
http://dx.doi.org/10.1371/journal.pone.0065329

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