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Assessing SNP-SNP Interactions among DNA Repair, Modification and Metabolism Related Pathway Genes in Breast Cancer Susceptibility
Genome-wide association studies (GWASs) have identified low-penetrance common variants (i.e., single nucleotide polymorphisms, SNPs) associated with breast cancer susceptibility. Although GWASs are primarily focused on single-locus effects, gene-gene interactions (i.e., epistasis) are also assumed t...
Autores principales: | Sapkota, Yadav, Mackey, John R., Lai, Raymond, Franco-Villalobos, Conrado, Lupichuk, Sasha, Robson, Paula J., Kopciuk, Karen, Cass, Carol E., Yasui, Yutaka, Damaraju, Sambasivarao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3670937/ https://www.ncbi.nlm.nih.gov/pubmed/23755158 http://dx.doi.org/10.1371/journal.pone.0064896 |
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