Innate immune response after adenoviral gene delivery into skin is mediated by AIM2, NALP3, DAI and mda5

Methods for human skin gene therapy requires efficient and stable introduction of genes into skin cells. Transient cutaneous gene therapy is an attractive approach in the treatment of skin diseases. The ‘Achilles heel’ of adenoviral gene therapy is its immunogenicity and many aspects of adenovirus i...

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Detalles Bibliográficos
Autores principales: Schulte, Matthias, Sorkin, Michael, Al-Benna, Sammy, Stupka, Jadwiga, Hirsch, Tobias, Daigeler, Adrien, Kesting, Marco Rainer, Steinau, Hans-Ulrich, Jacobsen, Frank, Steinstraesser, Lars
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing AG 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3671105/
https://www.ncbi.nlm.nih.gov/pubmed/23750330
http://dx.doi.org/10.1186/2193-1801-2-234

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3671105/
https://www.ncbi.nlm.nih.gov/pubmed/23750330
http://dx.doi.org/10.1186/2193-1801-2-234

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