RANKL Cytokine: From Pioneer of the Osteoimmunology Era to Cure for a Rare Disease

Since its identification, the RANKL cytokine has been demonstrated to play a crucial role in bone homeostasis and lymphoid tissue organization. Genetic defects impairing its function lead to a peculiar form of autosomal recessive osteopetrosis (ARO), a rare genetic bone disease presenting early in l...

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Detalles Bibliográficos
Autores principales: Lo Iacono, Nadia, Pangrazio, Alessandra, Abinun, Mario, Bredius, Robbert, Zecca, Marco, Blair, Harry C., Vezzoni, Paolo, Villa, Anna, Sobacchi, Cristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3671266/
https://www.ncbi.nlm.nih.gov/pubmed/23762088
http://dx.doi.org/10.1155/2013/412768

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