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Sitamaquine as a putative antileishmanial drug candidate: from the mechanism of action to the risk of drug resistance
Sitamaquine is a 8-aminoquinoline in development for the treatment of visceral leishmaniasis by oral route, no activity being observed on the experimental cutaneous leishmaniasis experimental models. Recent data explain how sitamaquine accumulate in Leishmania parasites, however its molecular target...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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EDP Sciences
2011
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3671420/ https://www.ncbi.nlm.nih.gov/pubmed/21678786 http://dx.doi.org/10.1051/parasite/2011182115 |