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Urea channel inhibitors (UCIs): A new functional class of aquaretics
Using large-scale small molecule screening techniques, Li et al. have identified a compound that inhibits the UT-B urea channel. They propose that this or similar compounds could be used as aquaretic agents to increase water excretion without changes in electrolyte excretion. Such compounds would po...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3671487/ https://www.ncbi.nlm.nih.gov/pubmed/23728001 http://dx.doi.org/10.1038/ki.2013.94 |