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Attenuating Cardiac Pulsations within the Cochlea: Structure and Function of Tortuous Vessels Feeding Stria Vascularis
The mammalian ear has an extraordinary capacity to detect very low-level acoustic signals from the environment. Sound pressures as low as a few μPa (−10 dB SPL) can activate cochlear hair cells. To achieve this sensitivity, biological noise has to be minimized including that generated by cardiovascu...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3671538/ https://www.ncbi.nlm.nih.gov/pubmed/23762624 http://dx.doi.org/10.1155/2013/941757 |
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author | Carraro, Mattia Negandhi, Jaina Kuthubutheen, Jafri Propst, Evan J. Kus, Lukas Lin, Vincent Y. W. Harrison, Robert V. |
author_facet | Carraro, Mattia Negandhi, Jaina Kuthubutheen, Jafri Propst, Evan J. Kus, Lukas Lin, Vincent Y. W. Harrison, Robert V. |
author_sort | Carraro, Mattia |
collection | PubMed |
description | The mammalian ear has an extraordinary capacity to detect very low-level acoustic signals from the environment. Sound pressures as low as a few μPa (−10 dB SPL) can activate cochlear hair cells. To achieve this sensitivity, biological noise has to be minimized including that generated by cardiovascular pulsation. Generally, cardiac pressure changes are transmitted to most peripheral capillary beds; however, such signals within the stria vascularis of the cochlea would be highly disruptive. Not least, it would result in a constant auditory sensation of heartbeat. We investigate special adaptations in cochlear vasculature that serve to attenuate cardiac pulse signals. We describe the structure of tortuous arterioles that feed stria vascularis as seen in corrosion casts of the cochlea. We provide a mathematical model to explain the role of this unique vascular anatomy in dampening pulsatile blood flow to the stria vascularis. |
format | Online Article Text |
id | pubmed-3671538 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | Hindawi Publishing Corporation |
record_format | MEDLINE/PubMed |
spelling | pubmed-36715382013-06-12 Attenuating Cardiac Pulsations within the Cochlea: Structure and Function of Tortuous Vessels Feeding Stria Vascularis Carraro, Mattia Negandhi, Jaina Kuthubutheen, Jafri Propst, Evan J. Kus, Lukas Lin, Vincent Y. W. Harrison, Robert V. ISRN Otolaryngol Research Article The mammalian ear has an extraordinary capacity to detect very low-level acoustic signals from the environment. Sound pressures as low as a few μPa (−10 dB SPL) can activate cochlear hair cells. To achieve this sensitivity, biological noise has to be minimized including that generated by cardiovascular pulsation. Generally, cardiac pressure changes are transmitted to most peripheral capillary beds; however, such signals within the stria vascularis of the cochlea would be highly disruptive. Not least, it would result in a constant auditory sensation of heartbeat. We investigate special adaptations in cochlear vasculature that serve to attenuate cardiac pulse signals. We describe the structure of tortuous arterioles that feed stria vascularis as seen in corrosion casts of the cochlea. We provide a mathematical model to explain the role of this unique vascular anatomy in dampening pulsatile blood flow to the stria vascularis. Hindawi Publishing Corporation 2013-05-19 /pmc/articles/PMC3671538/ /pubmed/23762624 http://dx.doi.org/10.1155/2013/941757 Text en Copyright © 2013 Mattia Carraro et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Carraro, Mattia Negandhi, Jaina Kuthubutheen, Jafri Propst, Evan J. Kus, Lukas Lin, Vincent Y. W. Harrison, Robert V. Attenuating Cardiac Pulsations within the Cochlea: Structure and Function of Tortuous Vessels Feeding Stria Vascularis |
title | Attenuating Cardiac Pulsations within the Cochlea: Structure and Function of Tortuous Vessels Feeding Stria Vascularis |
title_full | Attenuating Cardiac Pulsations within the Cochlea: Structure and Function of Tortuous Vessels Feeding Stria Vascularis |
title_fullStr | Attenuating Cardiac Pulsations within the Cochlea: Structure and Function of Tortuous Vessels Feeding Stria Vascularis |
title_full_unstemmed | Attenuating Cardiac Pulsations within the Cochlea: Structure and Function of Tortuous Vessels Feeding Stria Vascularis |
title_short | Attenuating Cardiac Pulsations within the Cochlea: Structure and Function of Tortuous Vessels Feeding Stria Vascularis |
title_sort | attenuating cardiac pulsations within the cochlea: structure and function of tortuous vessels feeding stria vascularis |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3671538/ https://www.ncbi.nlm.nih.gov/pubmed/23762624 http://dx.doi.org/10.1155/2013/941757 |
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