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The cannabinoid Δ(9)-tetrahydrocannabivarin (THCV) ameliorates insulin sensitivity in two mouse models of obesity

BACKGROUND: Cannabinoid type-1 (CB1) receptor inverse agonists improve type 2 diabetes and dyslipidaemia but were discontinued due to adverse psychiatric effects. Δ(9)-Tetrahydrocannabivarin (THCV) is a neutral CB1 antagonist producing hypophagia and body weight reduction in lean mice. We investigat...

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Detalles Bibliográficos
Autores principales:	Wargent, E T, Zaibi, M S, Silvestri, C, Hislop, D C, Stocker, C J, Stott, C G, Guy, G W, Duncan, M, Di Marzo, V, Cawthorne, M A
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2013
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3671751/ https://www.ncbi.nlm.nih.gov/pubmed/23712280 http://dx.doi.org/10.1038/nutd.2013.9

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