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The different radiosensitivity when combining erlotinib with radiation at different administration schedules might be related to activity variations in c-MET-PI3K-AKT signal transduction
OBJECTIVES: The aim of this paper was to investigate the efficacy and activity variation associated with phosphoinositide 3-kinase (PI3K) signal transduction when combining erlotinib with radiation, using different administration schedules. MATERIALS AND METHODS: Erlotinib was delivered to A973 canc...
Autores principales: | Zhuang, Hong-Qing, Bo, Qi-Fu, Yuan, Zhi-Yong, Wang, Jun, Zhao, Lu-Jun, Wang, Ping |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3671795/ https://www.ncbi.nlm.nih.gov/pubmed/23745052 http://dx.doi.org/10.2147/OTT.S44505 |
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