Cargando…
Associations of plasma atrial natriuretic peptide and electrolyte levels with essential hypertension
This study aimed to investigate the associations among the levels of plasma atrial natriuretic peptide (ANP) and electrolytes and essential hypertension (EH) in Uygur, Han and Kazakh populations in Xinjiang. A total of 724 hypertensive participants of different ethnicities from Xinjiang (208 Uygur,...
Autores principales: | , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3671822/ https://www.ncbi.nlm.nih.gov/pubmed/23737895 http://dx.doi.org/10.3892/etm.2013.991 |
_version_ | 1782272042901438464 |
---|---|
author | HU, GUANGMEI XU, XINJUAN LIANG, XIAOHUI YANG, XIAOPING ZHANG, JUNSHI SIMAYI, ZHULEPIYA CHEN, YULAN |
author_facet | HU, GUANGMEI XU, XINJUAN LIANG, XIAOHUI YANG, XIAOPING ZHANG, JUNSHI SIMAYI, ZHULEPIYA CHEN, YULAN |
author_sort | HU, GUANGMEI |
collection | PubMed |
description | This study aimed to investigate the associations among the levels of plasma atrial natriuretic peptide (ANP) and electrolytes and essential hypertension (EH) in Uygur, Han and Kazakh populations in Xinjiang. A total of 724 hypertensive participants of different ethnicities from Xinjiang (208 Uygur, 287 Han and 229 Kazakh) and 741 normal controls (208 Uygur, 267 Han and 266 Kazakh) were enrolled. The associations of ANP with serum potassium, serum sodium and blood pressure were assessed. In the normal control (NT) group, the concentration of ANP was higher in the Uygur population than in the Han population, and the concentration in the Han population was higher than that in the Kazakh population (P<0.05). In the EH group, the serum potassium levels of the Uygur and Han populations were higher than that of the Kazakh population (P<0.05). The ANP concentration in the Uygur ethnic group was higher than that in the Han population, which was in turn higher than that in the Kazakh participants (P<0.05). In the Kazakh population, the serum potassium level was significantly lower in the EH group compared with that in the NT group (P<0.05). The serum potassium level was significantly lower and the ANP concentration significantly higher in the EH group compared with those of NT groups in the Uygur and Han populations (P<0.05). Age and body mass index (BMI) were associated with hypertension in the Uygur, Han and Kazakh populations. Low serum potassium may be a risk factor of hypertension in individuals of Uygur and Kazakh ethnicity. Plasma ANP may be a regulatory factor involved in the development of hypertension in Uygur and Han populations. |
format | Online Article Text |
id | pubmed-3671822 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | D.A. Spandidos |
record_format | MEDLINE/PubMed |
spelling | pubmed-36718222013-06-04 Associations of plasma atrial natriuretic peptide and electrolyte levels with essential hypertension HU, GUANGMEI XU, XINJUAN LIANG, XIAOHUI YANG, XIAOPING ZHANG, JUNSHI SIMAYI, ZHULEPIYA CHEN, YULAN Exp Ther Med Articles This study aimed to investigate the associations among the levels of plasma atrial natriuretic peptide (ANP) and electrolytes and essential hypertension (EH) in Uygur, Han and Kazakh populations in Xinjiang. A total of 724 hypertensive participants of different ethnicities from Xinjiang (208 Uygur, 287 Han and 229 Kazakh) and 741 normal controls (208 Uygur, 267 Han and 266 Kazakh) were enrolled. The associations of ANP with serum potassium, serum sodium and blood pressure were assessed. In the normal control (NT) group, the concentration of ANP was higher in the Uygur population than in the Han population, and the concentration in the Han population was higher than that in the Kazakh population (P<0.05). In the EH group, the serum potassium levels of the Uygur and Han populations were higher than that of the Kazakh population (P<0.05). The ANP concentration in the Uygur ethnic group was higher than that in the Han population, which was in turn higher than that in the Kazakh participants (P<0.05). In the Kazakh population, the serum potassium level was significantly lower in the EH group compared with that in the NT group (P<0.05). The serum potassium level was significantly lower and the ANP concentration significantly higher in the EH group compared with those of NT groups in the Uygur and Han populations (P<0.05). Age and body mass index (BMI) were associated with hypertension in the Uygur, Han and Kazakh populations. Low serum potassium may be a risk factor of hypertension in individuals of Uygur and Kazakh ethnicity. Plasma ANP may be a regulatory factor involved in the development of hypertension in Uygur and Han populations. D.A. Spandidos 2013-05 2013-03-06 /pmc/articles/PMC3671822/ /pubmed/23737895 http://dx.doi.org/10.3892/etm.2013.991 Text en Copyright © 2013, Spandidos Publications http://creativecommons.org/licenses/by/3.0 This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited. |
spellingShingle | Articles HU, GUANGMEI XU, XINJUAN LIANG, XIAOHUI YANG, XIAOPING ZHANG, JUNSHI SIMAYI, ZHULEPIYA CHEN, YULAN Associations of plasma atrial natriuretic peptide and electrolyte levels with essential hypertension |
title | Associations of plasma atrial natriuretic peptide and electrolyte levels with essential hypertension |
title_full | Associations of plasma atrial natriuretic peptide and electrolyte levels with essential hypertension |
title_fullStr | Associations of plasma atrial natriuretic peptide and electrolyte levels with essential hypertension |
title_full_unstemmed | Associations of plasma atrial natriuretic peptide and electrolyte levels with essential hypertension |
title_short | Associations of plasma atrial natriuretic peptide and electrolyte levels with essential hypertension |
title_sort | associations of plasma atrial natriuretic peptide and electrolyte levels with essential hypertension |
topic | Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3671822/ https://www.ncbi.nlm.nih.gov/pubmed/23737895 http://dx.doi.org/10.3892/etm.2013.991 |
work_keys_str_mv | AT huguangmei associationsofplasmaatrialnatriureticpeptideandelectrolytelevelswithessentialhypertension AT xuxinjuan associationsofplasmaatrialnatriureticpeptideandelectrolytelevelswithessentialhypertension AT liangxiaohui associationsofplasmaatrialnatriureticpeptideandelectrolytelevelswithessentialhypertension AT yangxiaoping associationsofplasmaatrialnatriureticpeptideandelectrolytelevelswithessentialhypertension AT zhangjunshi associationsofplasmaatrialnatriureticpeptideandelectrolytelevelswithessentialhypertension AT simayizhulepiya associationsofplasmaatrialnatriureticpeptideandelectrolytelevelswithessentialhypertension AT chenyulan associationsofplasmaatrialnatriureticpeptideandelectrolytelevelswithessentialhypertension |