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NEXT-peak: a normal-exponential two-peak model for peak-calling in ChIP-seq data

BACKGROUND: Chromatin immunoprecipitation followed by high-throughput sequencing (ChIP-seq) can locate transcription factor binding sites on genomic scale. Although many models and programs are available to call peaks, none has dominated its competition in comparison studies. RESULTS: We propose a r...

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Detalles Bibliográficos
Autores principales: Kim, Nak-Kyeong, Jayatillake, Rasika V, Spouge, John L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3672025/
https://www.ncbi.nlm.nih.gov/pubmed/23706083
http://dx.doi.org/10.1186/1471-2164-14-349