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Molecular mechanisms of anti-tumor properties of P276-00 in head and neck squamous cell carcinoma
BACKGROUND: Tumors of the head and neck present aggressive pathological behavior in patients due to high expression of CDK/CCND1 proteins. P276-00, a novel CDK inhibitor currently being tested in clinic, inhibits growth of several cancers in vitro and in vivo. The pre clinical activity of P276-00 in...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3672051/ https://www.ncbi.nlm.nih.gov/pubmed/23414419 http://dx.doi.org/10.1186/1479-5876-11-42 |