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Molecular mechanisms of anti-tumor properties of P276-00 in head and neck squamous cell carcinoma

BACKGROUND: Tumors of the head and neck present aggressive pathological behavior in patients due to high expression of CDK/CCND1 proteins. P276-00, a novel CDK inhibitor currently being tested in clinic, inhibits growth of several cancers in vitro and in vivo. The pre clinical activity of P276-00 in...

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Detalles Bibliográficos
Autores principales:	Mishra, Prabha B, Lobo, Aurelio S, Joshi, Kalpana S, Rathos, Maggie J, Kumar, Gopinath A, Padigaru, Muralidhara
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3672051/ https://www.ncbi.nlm.nih.gov/pubmed/23414419 http://dx.doi.org/10.1186/1479-5876-11-42

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