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Suppressed Retinal Degeneration in Aged Wild Type and APPswe/PS1ΔE9 Mice by Bone Marrow Transplantation
Alzheimer's disease (AD) is an age-related condition characterized by accumulation of neurotoxic amyloid β peptides (Aβ) in brain and retina. Because bone marrow transplantation (BMT) results in decreased cerebral Aβ in experimental AD, we hypothesized that BMT would mitigate retinal neurotoxic...
Autores principales: | Yang, Yue, Shiao, Christine, Hemingway, Jake Frederick, Jorstad, Nikolas L., Shalloway, Bryan Richard, Chang, Rubens, Keene, C. Dirk |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3672108/ https://www.ncbi.nlm.nih.gov/pubmed/23750207 http://dx.doi.org/10.1371/journal.pone.0064246 |
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