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Epigenetic therapy in allogeneic hematopoietic stem cell transplantation
DNA methylation and other epigenetic phenomena appear to be relevant in the pathogenesis of several malignant disorders. DNA methyltransferases add methyl groups to cytosine-phosphate-guanine (CpG) islandsleading to gene promoter silencing. The DNA methyltransferases inhibitors azacitidine and decit...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Associação Brasileira de Hematologia e
Hemoterapia
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3672123/ https://www.ncbi.nlm.nih.gov/pubmed/23741191 http://dx.doi.org/10.5581/1516-8484.20130034 |