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Application of Hyperbranched Rolling Circle Amplification for Direct Detection of Mycobacterium Tuberculosis in Clinical Sputum Specimens

BACKGROUND: Global tuberculosis (TB) control is encumbered by the lack of a rapid and simple detection method for diagnosis, especially in low-resource areas. An isothermal amplification method, hyperbranched rolling circle amplification (HRCA), was optimized to detect Mycobacterium tuberculosis (Mt...

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Detalles Bibliográficos
Autores principales: Liu, Yang, Guo, Yan-Ling, Jiang, Guang-Lu, Zhou, Shi-Jie, Sun, Qi, Chen, Xi, Chang, Xiu-Jun, Xing, Ai-Ying, Du, Feng-Jiao, Jia, Hong-Yan, Zhang, Zong-De
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3672175/
https://www.ncbi.nlm.nih.gov/pubmed/23750210
http://dx.doi.org/10.1371/journal.pone.0064583