MeCP2 Regulates the Synaptic Expression of a Dysbindin-BLOC-1 Network Component in Mouse Brain and Human Induced Pluripotent Stem Cell-Derived Neurons

Clinical, epidemiological, and genetic evidence suggest overlapping pathogenic mechanisms between autism spectrum disorder (ASD) and schizophrenia. We tested this hypothesis by asking if mutations in the ASD gene MECP2 which cause Rett syndrome affect the expression of genes encoding the schizophren...

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Detalles Bibliográficos
Autores principales: Larimore, Jennifer, Ryder, Pearl V., Kim, Kun-Yong, Ambrose, L. Alex, Chapleau, Christopher, Calfa, Gaston, Gross, Christina, Bassell, Gary J., Pozzo-Miller, Lucas, Smith, Yoland, Talbot, Konrad, Park, In-Hyun, Faundez, Victor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3672180/
https://www.ncbi.nlm.nih.gov/pubmed/23750231
http://dx.doi.org/10.1371/journal.pone.0065069

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