Chemotherapy induced DNA damage response: Convergence of drugs and pathways

Chemotherapeutics target rapidly dividing cancer cells by directly or indirectly inducing DNA damage. Upon recognizing DNA damage, cells initiate a variety of signaling pathways collectively referred to as the DNA damage response (DDR). Interestingly, the pathways used to elicit this response are as...

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Detalles Bibliográficos
Autores principales: Woods, Derek, Turchi, John J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3672181/
https://www.ncbi.nlm.nih.gov/pubmed/23380594
http://dx.doi.org/10.4161/cbt.23761

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