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Self-Renewal of Single Mouse Hematopoietic Stem Cells Is Reduced by JAK2V617F Without Compromising Progenitor Cell Expansion

Recent descriptions of significant heterogeneity in normal stem cells and cancers have altered our understanding of tumorigenesis, emphasizing the need to understand how single stem cells are subverted to cause tumors. Human myeloproliferative neoplasms (MPNs) are thought to reflect transformation o...

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Detalles Bibliográficos
Autores principales:	Kent, David G., Li, Juan, Tanna, Hinal, Fink, Juergen, Kirschner, Kristina, Pask, Dean C., Silber, Yvonne, Hamilton, Tina L., Sneade, Rachel, Simons, Benjamin D., Green, Anthony R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3672217/ https://www.ncbi.nlm.nih.gov/pubmed/23750118 http://dx.doi.org/10.1371/journal.pbio.1001576

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