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Intermolecular domain docking in the hairpin ribozyme: Metal dependence, binding kinetics and catalysis

The hairpin ribozyme is a prototype small, self-cleaving RNA motif. It exists naturally as a four-way RNA junction containing two internal loops on adjoining arms. These two loops interact in a cation-driven docking step prior to chemical catalysis to form a tightly integrated structure, with dramat...

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Detalles Bibliográficos
Autores principales:	Sumita, Minako, White, Neil A., Julien, Kristine R., Hoogstraten, Charles G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Landes Bioscience 2013
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3672286/ https://www.ncbi.nlm.nih.gov/pubmed/23324606 http://dx.doi.org/10.4161/rna.23609

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