Re-evaluating high-frequency oscillation for ARDS: Would a targeted approach be successful?

High-frequency oscillatory ventilation (HFOV) seems ideal for lung protection in acute respiratory distress syndrome, but randomized trials have not shown a mortality reduction. The initial oxygenation response to HFOV appears to be associated with survival. Here, we discuss the mechanisms of oxygen...

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Detalles Bibliográficos
Autores principales: Goligher, Ewan C, Ferguson, Niall D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Editorial
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3672488/
https://www.ncbi.nlm.nih.gov/pubmed/23601696
http://dx.doi.org/10.1186/cc12602
Descripción
Sumario:High-frequency oscillatory ventilation (HFOV) seems ideal for lung protection in acute respiratory distress syndrome, but randomized trials have not shown a mortality reduction. The initial oxygenation response to HFOV appears to be associated with survival. Here, we discuss the mechanisms of oxygenation response to increases in airway pressure and the interpretation of the oxygenation response observed in the present study.

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