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Protease-activated receptor-1 impairs host defense in murine pneumococcal pneumonia: a controlled laboratory study

INTRODUCTION: Streptococcus pneumoniae is the most common causative pathogen in community-acquired pneumonia. Protease-activated receptor-1 (PAR-1) is expressed by multiple cell types present in the lungs and can be activated by various proteases generated during acute inflammation. The cellular eff...

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Detalles Bibliográficos
Autores principales:	Schouten, Marcel, van't Veer, Cornelis, Roelofs, Joris JTH, Levi, Marcel, van der Poll, Tom
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3672627/ https://www.ncbi.nlm.nih.gov/pubmed/23270594 http://dx.doi.org/10.1186/cc11910

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