Parity induces differentiation and reduces Wnt/Notch signaling ratio and proliferation potential of basal stem/progenitor cells isolated from mouse mammary epithelium

INTRODUCTION: Early pregnancy has a strong protective effect against breast cancer in humans and rodents, but the underlying mechanism is unknown. Because breast cancers are thought to arise from specific cell subpopulations of mammary epithelia, we studied the effect of parity on the transcriptome...

Descripción completa

Detalles Bibliográficos
Autores principales: Meier-Abt, Fabienne, Milani, Emanuela, Roloff, Tim, Brinkhaus, Heike, Duss, Stephan, Meyer, Dominique S, Klebba, Ina, Balwierz, Piotr J, van Nimwegen, Erik, Bentires-Alj, Mohamed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3672662/
https://www.ncbi.nlm.nih.gov/pubmed/23621987
http://dx.doi.org/10.1186/bcr3419

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3672662/
https://www.ncbi.nlm.nih.gov/pubmed/23621987
http://dx.doi.org/10.1186/bcr3419

Ejemplares similares